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EC number: 232-565-6
CAS number: 9000-90-2
Studies for terrestrial toxicity have been waived based on the following
Alpha-amylase has a very low Henry’s law constant (<10-4)
and a low octanol-water partition coefficient (<0). Therefore, exposure
to agricultural soil via sludge application as well as via aerial
deposition is very low. Exposure to soil may occur if waste water is
discharged off via septic tank. According to the EUSES calculations,
less than 0.01% of enzymes entering a sewage treatment plant (STP) will
bind to sludge. As enzymes are degradable at both aerobic and anaerobic
conditions, a high rate of inactivation and degradation of alpha-amylase
in soil is expected. Assuming a degradation rate in soil at the same
level as degradation rate in surface water, i.e. a half life of 5 hours,
calculations show that the risk characterization ratio (RCR) for soil is
25% below the RCR for the surface water. Thus alpha-amylase applied to
agricultural soils via sludge application do not present a risk to the
soil compartment due to sludge application. Enzymes may potentially
leach into the soil, if waste water is discharged to a septic tank. The
chemical safety assessment based on the equilibrium partitioning method
shows that alpha-amylase does not exhibit a risk to soil living
organisms in such situation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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