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EC number: 265-191-7
CAS number: 64742-88-7
A complex combination of hydrocarbons obtained from the distillation of crude oil or natural gasoline. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C9 through C12 and boiling in the range of approximately 140°C to 220°C (284°F to 428°F).
In the key dermal photoirritation study, the irritation index is 4.8 for Jet fuel A-1 exposed to UV A light and 4.1 for Jet fuel A-1 not exposed to UV A light. Therefore, the photoirritation index is 0.7 and the test substance is not considered a photoirritant.
In a key
dermal photoirritation study (Klimisch score=1; ARCO, 1992y), five
female New Zealand White rabbits were exposed to 0.3 mL of undiluted
thermocracked kerosine on two intact areas of the skin for one hour.
Concurrent positive and untreated controls were also applied to two
intact areas. After test article or positive control exposure, half of
the sites were exposed to UV A light for 5.9 hours and were observed 30
minutes, 24, 48, and 72 hours after UV A exposure. Irritation and
photoirritation were scored using the Draize scoring method. The
positive control induced an appropriate response with a photoirritation
index of 4.4 and is considered a moderate photoirritant. The
photoirritation index for thermocracked kerosine is 1.5 and is therefore
considered to be a slight photoirritant, under the conditions of this
supporting photoirritation studies (ARCO, 1992z; ARCO 1992aa; ARCO
1991b) , undiluted straight run kerosine and Jet fuel A-1 was applied
to two sites on the shorn skin of each of 5 female rabbits. A 1%
solution (0.3 mL) of 8-methoxypsoralen (MOP) was applied to two
different sites on each of the rabbits. Two sites received no test
material and these served as negative control sites. One hour after
application of test material or MOP, wrappings were removed and any
residual test or positive control material was wiped from the skin. One
each of the test sites, positive control sites and negative control
sites were then covered with a light-impervious material and he animals
were then exposed to 10J/cm² of UV A light for 5.9 hours. After the
exposure to UV A, sites were examined for responses 30 minutes, 24,
48 and 72 hours. Skin responses were evaluated and scored using the
the first study, the irritation index was 4.2 for
straight run kerosine exposed to UVA and 4.3 for straight run kerosine
not exposed to UVA; therefore, the photoirritation index is -0.1. Under
the conditions of this study the test material is considered a
non-irritant. In the second study, the
irritation index is 4.7 for straight run kerosine exposed to UVA and 3.7
for straight run kerosine not exposed to UVA ; therefore, the
photoirritation index is 1.0. Under the conditions of this study, the
test article is classified as a slight photoirritant. The
irritation index is 4.8 for Jet fuel A-1 exposed to UV A light and 4.1
for Jet fuel A-1 not exposed to UV A light. Therefore, the
photoirritation index is 0.7 and the test substance is not considered a
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