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EC number: 224-292-6
CAS number: 4292-10-8
Short-term toxicity to aquatic
Taking into account all acute aquatic
toxicity data (fish, daphnia and algae) it is the registrants expert
judgement that C12 AAPB is toxic to aquatic organism, corresponding to
Acute Cat. 2 according to the Global Harmonized System (GHS/UN). As this
building block is not implemented in Europe, it is not appropriate to
classify C12 AAPB for acute aquatic effects.
Fish: LC50(96 h) = 1.1 mg/L
Invertebrate: EC50(48 h) = 1.9 mg/L
Algae or aquatic plants: ErC50= 1.5
Long-term toxicity to aquatic
Fish: 37 d/100 d NOEC=0.135 mg/L
Invertebrate: 21 d NOEC=0.3 mg/L
Algae or aquatic plants: 72 h NOEC=0.3
Biodegradation in water: Readily
Bioaccumulation: BCF < 71
logKow: 3.54 (calculated, weighted
layer: Based on the very low vapour pressures of the ionic
substances, the atmosphere is not the target compartment of
environmental distribution. The registration substance is not expected
to reach the atmospheric stratosphere in appreciable amounts where it is
rapidly degraded by reaction with OH radicals and therefore is not
expected to present a danger to the structure and/or the functioning of
the stratospheric ozone layer.
The substance is readily
biodegradable. The ready biodegradability of the substance was proven in
a number of tests conducted under different conditions (aerobic,
anaerobic, marine conditions). Toxicity towards aquatic micro-organisms
is expected to be of no concern for sewage treatment plants. Long-term
exposure of aquatic organisms is therefore unlikely.
Bioaccumulation in organisms is
considered to be low. Therefore, secondary poisoning through the food
chain is of no concern for the registration substance.
The exposure and uptake of the
substance by soil dwelling organisms is unlikely as the target
compartment of discharge and environmental distribution is the
hydrosphere and the substance is readily biodegradable. Sediment
dwelling organisms may be exposed to the test substance, but it can be
assumed that the test substance especially the long-chain members are
adsorbed onto sediment organic matter and therefore bioavailability will
be reduced. Furthermore, based on the available data, bioaccumulation is
expected to be low and the test substance proved to be (readily)
biodegradable under different conditions (marine water, aerobic,
The following data were taken into
account for the calculation of sediment and soil PNECs using the
equilibrium partitioning method:
1E-06 h Pa at 25°C
250 mg/L at 20°C
3.54 at 20°C
1.029 mg/kg dwt
0.103 mg/kg dwt
0.198 mg/kg dwt
into account all acute aquatic toxicity data (fish, daphnia and algae)
it is the registrants expert judgement that C12 AAPB is toxic to aquatic
organism, corresponding to Acute Cat. 2 according to the Global
Harmonized System (GHS/UN). As this building block is not implemented in
Europe, it is not appropriate to classify C12 AAPB for acute aquatic
C12 AAPB proved to be readily biodegradable.
According to GHS Regulation EC No 1272/2008,
C12 AAPB does not need to be classified with regard to acute
C12 AAPB is classified as hazardous to
the aquatic environment (long-term) Aquatic Chronic 3. C12 AAPB
does not need to be classified as 'hazardous to the ozone layer'.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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