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EC number: 285-597-8
CAS number: 85117-47-1
The test material was not genotoxic to Salmonella and E. Coli strains
with and without metabolic activation.
No cytotoxic response was seen in the dose range finding study.
The positive control exhibited at least a 3 fold increase in revertant
Additional information from genetic toxicity in vitro:
All of the data available for the registered substance to assess the
mutagenic, clastogenic and genotoxic effects
of the substance in vitro and in vivo. All the studies achieved negative
Data have been included that were conducted on sodium and magnesium
salts. The sodium and magnesium ions
are considered likely to be more active than calcium and the data is
therefore considered suitable as supporting
data for the endpoint.
The following information is taken into account for any hazard / risk
A number of genotoxicity studies have been conducted in vitro and in
vivo to determine the genotoxic effects of
the registered substance
Justification for selection of genetic toxicity endpoint
Based on the in vitro and in vivo data available for the substance, the
substance is considered to be not
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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