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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Study meets criteria for Klimisch score 2 because it generally follows an internationally recognised method (EPA OTS 797.1050) and was carried out to Good Laboratory Practice. However, there was no analytical confirmation of the test concentrations. In addition, only 2 replicates per concentration were used and test vessels containing 1000 mg/l nominal WAF loadings were slightly cloudy at the start of the test and at 24 hours.

Key value for chemical safety assessment

EC50 for freshwater algae:
1 000 mg/L
EC10 or NOEC for freshwater algae:
1 000 mg/L

Additional information

The EC50 in freshwater algae is considered to be >1000mg/l. Two of the studies available support this

conclusion, while the one remaining study did not exceed 100 mg/l, although the data support the conclusion

that the EC50 is above this dose level. As this dose level has been included in the other studies conducted, it is

considered acceptable to consider this as supporting data but to conclude that the highest dose level attained

from studies considered reliable is both appropriate and adequately supported by the data.

The substance is, therefore, considered not toxic to algae. Nevertheless, adequate controls will be in place

during production and use to ensure that the substance is not released to the environment.

The toxicity of the substance has not been assessed using marine algal species, but it is considered likely to be

similar to freshwater species.

The following information is taken into account for effects on algae / cyanobacteria for the derivation of PNEC:

The toxicity of the substance has been measured experimentally with freshwater algae. Due to the extremely low

water solubility all studies have been conducted using Water Accomodated Fractions and completed as limit