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EC number: 285-597-8
CAS number: 85117-47-1
Table 2: Number
of animals dead [and with evident toxicity] [and time range within which
Mortality (# dead/total)
Time range of deaths (hours)
Number with evident toxicity (#/total)
an acute oral toxicity study, groups of Sprague-Dawley
rats (5/sex) were
given a single oral dose of sodium 4-icosylbenzenesulfonate at doses of
0 or 5000 mg/kg bw and observed for 14 days.
mortality occurred in this limit test, therefore an LD50 has not been
acute oral study is classified as acceptable. It satisfies the guideline
requirement for an acute oral study OECD 401 in the rat.
Concentrations, exposure conditions and number of evident toxicity per
Analytical Conc. (mg/L)
an acute inhalation toxicity study, groups of young adult Sprague Dawley
rats (5/sex) were exposed by inhalation route for 4 hours via whole body
exposure to petroleum derived calcium
concentrations of 1.9 mg/L. Animals then were observed for 14 days.
mortality occurred in this limit test, therefore an LC50 has not been
determined. This acute inhalation study is classified as acceptable. It
satisfies the guideline requirement for an acute inhalation study in the
See attached study report for details
During exposure of the substance by the oral, dermal and inhalation
routes only a minor incidence of mortality
was observed and never at a rate considered to be significant when
dosing levels at or below the volumes
specified above. Where significant mortality has been observed, this was
observed at dose levels significantly
higher than those specified above. The limit values expressed above are,
therefore, considered appropriate.
Justification for selection of acute toxicity – oral endpoint
Mortality did not occur at doses of 5000 mg/kg bw, therefore, and LD50 was not determined.
Justification for selection of acute toxicity – inhalation endpoint
Mortality did not occur at doses of 1.9 mg/l, therefore, an LC50 cannot be determined.
Justification for selection of acute toxicity – dermal endpoint
Mortality did not occur at doses of 5000 mg/kg bw, therefore an LD50 was not determined.
As not significant mortality has been observed at the limit values
expressed above, the substance is considered
to be not classified as acutely toxic.
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