Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 292-429-7 | CAS number: 90622-29-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Alchisor CAL 145 comprises alkenes C13-14 hydroformylation products with read-across from the chemically-similar Alchisor CAL 123 as defined in the `Read-Across Justification Document'. Where environmental toxicity data exist for Alchisor CAL 123, these are representative of the Alchisor CAL 145 substance.
In accordance with REACH Annex IX, the requirement for studies of the effects on terrestrial organisms is waived on the basis of unlikely direct and indirect exposure of the soil compartment. No reliable measured terrestrial ecotoxicity data are available for Alchisor CAL 145.
Key value for chemical safety assessment
Additional information
Alchisor CAL 145 comprises alkenes C13-14 hydroformylation products with read-across from the chemically-similar Alchisor CAL 123 as defined in the `Read-Across Justification Document'. Where environmental toxicity data exist for Alchisor CAL 123, these are representative of the Alchisor CAL 145 substance. In accordance with REACH Annex IX, the requirement for studies of the effects on terrestrial organisms is waived on the basis of unlikely direct and indirect exposure of the soil compartment. In addition, other evidence presented in this dossier on the substance's ready biodegradability, low toxicity to aquatic organisms and the absence of toxicity to mammals further support the waiver. No reliable measured terrestrial ecotoxicity data are available for Alchisor CAL 145.
Exposure to Soils
It is unlikely that soil organisms will be exposed to Alchisor CAL 145 as there is no intended use involving the direct application of Alchisor CAL 145 to soil. In addition, it is unlikely that indirect exposure will occur, via the application of sewage sludge to land, as Alchisor CAL 145 is expected to biodegrade through the sewage treatment process.
Biodegradation
The chemically-similar Alchisor CAL 123 has been shown in the reliable (Klimisch 1; Klimisch 2 when used for read-across) study by Schaefer and Matthews (2010) to be readily biodegradable in water. The test substance biodegraded to an extent of 87.7% after 28 days and although the biodegradation rate just missed the 10-day window threshold, this aspect of the test is not applicable to mixtures where different components of the mixture can biodegrade preferentially (reference TG 103C). It is assumed that Alchisor CAL 145 will readily biodegrade in the environment and sewage treatment processes and be unavailable for uptake by soil organisms.
Toxicity to Aquatic Organisms
The toxicity of the chemically-similar Alchisor CAL 123 to aquatic organisms is very low based on the evidence presented in this dossier. The lowest measured toxicity was based on an algal test where the NOEL based on algal growth was 25 mg/L. Acute toxicity to invertebrates and fish was >100 mg/L based on 50% mortality. It is reasonable to assume that Alchisor CAL 145 will also exhibit similar toxicities to soil organisms resulting in a low hazard, which is not considered to be toxic (in PBT terms) to terrestrial life.
Toxicity to Mammals
Alchisor CAL 123 is not considered to be toxic to mammals based on the evidence presented in this dossier. Acute oral and acute dermal toxicities in rat were > 2000 and >2020 mg/kg, respectively based on the study by Kuhn (2010). Using this evidence it is assumed that Alchisor CAL 145 is not considered to be toxic (in PBT terms) to mammals and secondary poisoning is unlikely to occur in the environment.
In summary, the data requirement for terrestrial ecotoxicity testing is waived on the evidence of lack of direct or indirect exposure to soil organisms, ready biodegradability in the environment and the absence of toxicity in aquatic organisms and mammals.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.