Registration Dossier
Registration Dossier
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EC number: 292-429-7 | CAS number: 90622-29-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
One reliable (Klimisch 1; Klimisch 2 when used for read-across) toxicity study for aquatic algae was available for Alchisor CAL 123 with read-across to Alchisor CAL 145. The toxicity of Alchisor CAL 123 to Pseudokirchnerella subcapitata was reported by Porch & Krueger (2010) in an OECD 201 guideline and GLP compliant study. Algae was exposed to toxicant in measured concentrations for 72 hours, resulting in a 72-hr LC50 of 35 mg/L, based on cell density and yield. The 72-hr NOEC, based on growth rate, was 25 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 35 mg/L
- EC10 or NOEC for freshwater algae:
- 25 mg/L
Additional information
Alchisor CAL 145 comprises alkenes C13-14 hydroformylation products and read-across from the chemically-similar Alchisor CAL 123 has been used in this hazard assessment as defined in the `Read-Across Justification Document'. One reliable (Klimisch 1; Klimisch 2 when used for read-across) toxicity study for aquatic algae was available for Alchisor CAL 123. The toxicity of Alchisor CAL 123 to Pseudokirchnerella subcapitata was reported by Porch & Krueger (2010) in an OECD 201 guideline and GLP compliant study. Algae was exposed to toxicant in measured concentrations for 72 hours, resulting in a 72-hr LC50 of 35 mg/L, based on cell density and yield. The 72-hr NOEC, based on growth rate, was 25 mg/L. This reliable study result is designated as Key for the toxicity to aquatic algae endpoint.
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