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EC number: 292-429-7
CAS number: 90622-29-0
Table #1: Irritant/corrosive response
data for each animal at each observation time up to removal of each
animal from the test
Score at time point / Reversibility
Max. score: 4
Average 24h, 48h, 72h
Average time (unit) for reversion
*) Reversibility: c. = completely
reversible; n.c. = not completely reversible; n. = not reversible
A primary dermal irritation study was conducted in three
albino rabbits using test substance Alkenes, C11 -12, hydroformylation products,
distn. residues (CAS No: 90622 -27 -8). There was one intact test site
per animal. Each test site was treated with 0.5 mL of the undiluted test
substance and covered with a semi-permeable dressing. The test substance
was maintained in contact with the skin for 4 hours. Observations for
dermal irritation and defects were made at 1, 24, 48 and 72 hours after
removal of the dressings. Erythema and edema were not observed at any
time throughout the study. No other signs of irritation were observed
during the study. One animal was found dead on Day 1 of the study; the death
was not considered related to the administration of the test substance. A
replacement animal was dosed. Based on the Primary Irritation Index
(PII) of 0.0, the test substance was rated non-irritating.
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