Registration Dossier
Registration Dossier
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EC number: 417-040-3 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The study was conducted in accordance with OECD Guideline for Testing of Chemicals No. 209 and EEC Methods for the Determination of Ecotoxicity, EEC Directive 67/548 Annex vm Part C (87/302/EEC), Activated Sludge, Respiration Inhibition Test.
The EC50 (respiration inhibition) values for Coagulant 122 (solid) with activared sewage sludge has been determined as > 100 mg(total solids)/l for the 3 hours contact time.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
Additional information
The oxygen consumption rates for the control, test and reference cultures after 3 hours contact time are given in Table, together with percent inhibition values.
| Culture | Concentration mg/l | O2 consumption rates mgO2/l/min | % inhibition | |
Control |
R1 | - | 0.50 | - |
| R2 | - | 0.47 | - | |
Test |
R1 | 100* | 0.46 | 5 |
| R2 | 100* | 0.47 | 3 | |
Reference |
3.2 | 0.36 | 26 | |
| 10 | 0.24 | 51 | ||
| 32 | 0.11 | 71 | ||
Percent inhibition is plotted against concentration in Figures 1 full document (reference culture) and the EC50 values for 3 hours contact time, derived by interpolation, are given below:
Coagulant 122 (solid): EC50 (3 hours): > 100 mg(total solids)/1
3,5-dichlorophenol: EC50 (3 hours): 9.4 mg/1.
Variation in respiration rates of Controls 1 and 2: ± 3%.
The validation criteria for (i) Control culture respiration and (ii) respiration inhibition by the reference substance, were fulfilled during this study.
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