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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1995
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Principles of method if other than guideline:
Handbook data
GLP compliance:
not specified
Type of method:
other: not specified
Partition coefficient type:
octanol-water
Analytical method:
not specified
Type:
log Pow
Partition coefficient:
0.33
Remarks on result:
other: experimental database match of the QSAR model software EpiSuite v.4.1; temperature not reported but room temperature assumed.
Conclusions:
According to an experimental database match (Hansch, C. et al. 1995) of the QSAR model software EpiSuite v.4.1, propionic acid (SMILES code: CCC(=O)O) has a log Kow of 0.33 (no temperature provided) whereas the log Kow estimated with KOWWIN v1.68 amounts to 0.58 at 25°C.

Description of key information


The log Kow of the substance is 0.33 at 25 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):
0.33
at the temperature of:
25 °C

Additional information