Registration Dossier
Registration Dossier
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EC number: 939-125-9 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
There are no data available on the toxicity to aquatic microorganisms of hydrolysis products of 3-(triethoxysilyl)propan-1-amine (where the concentration range of 3-(triethoxysilyl)propan-1-amine is > 0.1% - <16% (w/w)) EC no. 939-125-9). In order to fulfil the standard information requirements set out in Annex VIII, read-across from a structurally related substance (3-(triethoxysilyl)propan-1-amine, CAS no. 919-30-2), is conducted in accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006.
This read-across is based on the hypothesis that the starting material, 3-(triethoxysilyl)propan-1-amine, hydrolyses rapidly in water resulting in the target substance. It can be expected that both the target and the source substance product have similar behaviour under the aqueous conditions. The target substance consists of the hydrolysis product 3-aminopropylsilanetriol and condensation products dimers, trimers and polymers of siloxanes which have similar functional groups (-O-Si- or HO-Si-). Therefore, it is considered that the target substance and 3-(triethoxysilyl)propan-1-amine are in one class of compounds and structural differences are not supposed to contribute to significant differences in activity with respect to eco- and human toxicological endpoints. The other hydrolysis product is ethanol which is well described in the public domain to have no adverse environmental effects.
The toxicity of 3-(triethoxysilyl)propan-1-amine (CAS no. 919-30-2) to aquatic microorganisms has been investigated on three trophic levels i.e. fish, aquatic invertebrates and algae. In none of these tests acute toxic effects were observed (L(E)C50 > 100 mg/L). In an oxygen consumption test with Pseudomonas putida, an EC50 of 43 mg/L was determined for the parent material. It is very likely that this effect concentration reflects rather a worst case approach, as a single microorganism strain was tested individually.
In conclusion, 3-(triethoxysilyl)propan-1-amine (CAS no. 919-30-2) and thereby the target substance hydrolysis products of 3-(triethoxysilyl)propan-1-amine > 0.1% - <16%
(EC no. 939-125-9) can be regarded as not hazardous to the aquatic environment.
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