Registration Dossier
Registration Dossier
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EC number: 250-439-9 | CAS number: 31027-31-3
Endpoint summary
Administrative data
Description of key information
skin irritation: according OECD guideline test, result: subtance is corrosive
eye irritation: according OECD guideline test; result: substance is irritating
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
In 2 guideline studies p-isoprpylphenyl isocyanate was found corrosive to the skin.
In a guideline study on eye irritation, p-isopropylphenyl isocyanate was found irritant
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: irritating
Justification for classification or non-classification
due to the results of the key study for skin irritation/corrosion cat 1C (H314; causes severe burns and eye damage) is justified
due to the severe effects on the eye "Eye Damage Cat 1" (H318 causes serious eye damage) is adequate.
The compound will also be classified with STOT Single Exp. 3.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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