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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Description of key information

Hydrolysisas a Function of pH

Key value for chemical safety assessment

Half-life for hydrolysis:
2 720 d
at the temperature of:
25 °C

Additional information

FR-513 was determined to be hydrolytically stable across the range of environmentally relevant pH at 25°C. The half-life of FR-513 at pH 4 and 7 was estimated to be greater than 1 year as determined by 5-day incubations at 50 °C. FR-513 was found to be hydrolytically active only in pH 9 aqueous buffer at elevated temperatures. Definitive testing at three elevated temperatures (40, 50 and 60 °C) showed a very strong temperature dependence of FR-513 hydrolysis at pH 9. Two hydrolytic degradants - DBMO and bromide - were detected and measured. Using the Arrhenius equation and the results from these elevated temperatures, the calculated hydrolysis rate constant for FR-513 at pH 9 and 25°C was extrapolated as 2.55 x 10-4 day-1, corresponding to a half-life of 2.72 x 103 days (approximately 7.5 years).