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EC number: 253-057-0
CAS number: 36483-57-5
Skin irritation in rabbitsEye irritation in rabbits
Skin irritation: FR-513 was found to have no effect on rabbit skin when
applied onto clipped skin for 4 hr. Based on the study FR-513 was found
to be non-irritant to the rabbits under the conditions of the study.
Eye irritation: FR-513 was found to have effects on the eyes of the
rabbits which completely resolved after 7 or 14 days in two animals. In
one aminal some of the effects persisted until 21 days (the maximum
observation period). Based on the results of this study the substance is
considered highly irritating and as such classified in the EU.
Based on the results of the acute irritation to eye study, FR-513 is
considered highly irritating and as such classified under the EEC
criteria for classification and labelling requirements for Dangerous
Substances and Preparations (67/548/EEC) and the CLP Regulation (EC No
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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