Registration Dossier
Registration Dossier
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EC number: 204-198-1 | CAS number: 117-57-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
- Principles of method if other than guideline:
- No information provided
- GLP compliance:
- no
- Remarks:
- Study conducted prior to implementation of GLP
- Test type:
- concentration x time method
Test material
- Reference substance name:
- 3-hydroxy-2-methylquinoline-4-carboxylic acid
- EC Number:
- 204-198-1
- EC Name:
- 3-hydroxy-2-methylquinoline-4-carboxylic acid
- Cas Number:
- 117-57-7
- Molecular formula:
- C11H9NO3
- IUPAC Name:
- 3-hydroxy-2-methylquinoline-4-carboxylic acid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: dust
- Type of inhalation exposure:
- not specified
- Vehicle:
- air
- Details on inhalation exposure:
- GENERATION OF TEST ATMOSPHERE / CHAMBER DESCRIPTION
- Temperature in air chamber: 20°C
VEHICLE
- Composition of vehicle: air (not further specified) - Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- >= 3 - <= 480 min
- Concentrations:
- not specified (air passed through 5 cm layer of test substance)
- No. of animals per sex per dose:
- 12 animals (sex not specified)
- Control animals:
- not specified
Results and discussion
Effect levels
- Remarks on result:
- other: No LC50 determined
- Mortality:
- none
- Clinical signs:
- other: none
- Body weight:
- not specified
- Gross pathology:
- none
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Inhalation of 3-hydroxy-2-methylquinoline-4-carboxylic acid showed no effects.
- Executive summary:
In an acute inhalation to 3-hydroxy-2-methylquinoline-4-carboxylic acid in air for up to 8 hours.
During the observation period, no death occurred and no clinical signs or gross pathological evidence was observed.
Mortality (rats): none
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