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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
Deviations:
no
GLP compliance:
yes
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, non-adapted
Details on inoculum:
Municipal activated sludge from laboratory wastewater treatment plants fed with
municipal and synthetic sewage. Concentration of dry substance 30 mg/l.
Duration of test (contact time):
28 d
Initial conc.:
>= 98.4 - <= 102 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Reference substance:
aniline
Parameter:
% degradation (O2 consumption)
Value:
> 0 - < 10
Sampling time:
28 d
Parameter:
ThOD
Value:
1 702 mg O2/g test mat.
Results with reference substance:
Aniline reached a plateau after 14 days at about 80%.

Detailed results: Biodegradation in relation to the ThOD [%]

RS = reference substance, IH = inhibiton control, PC = abiotic elimination, TS = test substance

Date       Days       RS      IH      PC     TS1     TS2    TS3    TS4     TS5    TS6    TS7

30.12.98       0        0        0        0        0        0        0         0        0        0        0

31.12.98       1       -3       -1       0        -4       -3       -4       -3       -4       -4       -3

1.1.99        2       -4       -2       0        -4       -4       -5       -5       -5       -4       -4

2.1.99        3       -5       -2       0        -5       -4       -7       -6       -6       -4       -5

3.1.99        4       -4        5       0        -7       -5       -8       -6       -6       -4        -5

4.1.99        5       -1        5       ---      -6       -4       -7       -7       -6       -3        -6

5.1.99        6        8        4       ---       -6       -5        -8       -8       -6       -3       -7

6.1.99        7       47       6       ---       -6       -4        -8       -8       -6       -2       -6

7.1.99        8       60       7       ---       -6       -4        -9       -8       -6       -2       -7

8.1.99        9       62       9       ---       -7       -5       -11       -9       -7       -2       -8

9.1.99        10       68       10       ---      7       -5       -11       -9       -7       -1       -8

10.1.99       11       70       12       ---     -7       -5       -11       -10       -8     -1       -7

11.1.99       12       71       13       ---      7       -5       -12       -10       -8       0       -8

12.1.99       13       72       15       ---      -6       -4       -12       -10       -8       1       -8

13.1.99       14       72       16       ---      -7       -5       -11       -10       -8       1       -9

14.1.99       15       72       20       ---      -5       -4       -11       -10       -8       2       -9

15.1.99       16       73       32       ---      -5       -4       -11       -10       -8       2       -9

16.1.99       17       73       33       ---      -6       -5       -12       -11       -8       2       -9

17.1.99       18       74       35       ---      -6       -5       -12       -11       -8       3       -9

18.1.99       19       73       35       ---      -5       -5       -12       -12       -8       3       -10

19.1.99       20       74       35       ---      -5       -5       -12       -12       -8       4       -9

20.1.99       21       74       36       ---      -5       -6       -13       -12       -8       4       .9

21.1.99       22       74       35       ---      -4       -5       -14       -12       -8       4       -10

22.1.99       23       74       36       ---      -5       -6       -14       -13       -9       4       -10

23.1.99       24       74       36       ---      -4       -6       -14       -13       -9       5       -10

24.1.99       25       74       36       ---      -3       -6       -14       -13       -9       5       -11

25.1.99       26,       74       36       ---      -4       -7       -14       -13       -9       5       -0

26.1.99       27      74       36       ---      -3       -8       -15       -14       -9       5       -11

27.1.99       28       75       36       ---      - 3       -6    -15        -13       -9       5       -11

Validity criteria fulfilled:
yes
Remarks:
reference substance Aniline showed a degradation of about 80% after 28 days.
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
The substance is not readily biodegradable.
Executive summary:

In a test according to OECD 301 F (manometric respiration test) the substance 3-hydroxy-2-methylquinoline-4-carboxylic acid did not show relevant signs of biodegradation. It is therefore considered to be not readily biodegradable.

Description of key information

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information