Bis(2-hydroxyethyl) sulphone

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

The study was conducted between 6 March 1998 and 17 May 1998

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: OECD draft guideline July 1997):Estimation of the Adsorption Coefficient (K0c) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC).

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

GLP compliance:

yes (incl. QA statement)

Type of method:

HPLC estimation method

Media:

other: methanol

Specific details on test material used for the study:

Sponsor's identification: BHES-100X
Batch number: 1A0110
Date received: 20 January 1998
Storage conditions: room temperature in the dark

Radiolabelling:

no

Test temperature:

Column temperature: 40°C

Details on study design: HPLC method:

EQUIPMENT
- Apparatus:
HPLC system: Hewlett-Packard 1050, incorporating autosampler and workstation
Column: Hypersil CN-BDS (250 x 4.6 mm id)
Column temperature: 40°C
Flow-rate: 1.0 ml/min
UV detector wavelength: dead ti me and reference standards: 210 nm
sample: 212 nm


MOBILE PHASES
- Type: methanol:water (55:45 v/v)
- Experiments with additives carried out on separate columns: yes / no
- pH: 6.2
- Solutes for dissolving test and reference substances: Test material and reference standards were prepared in methanol

DETERMINATION OF DEAD TIME
- Method: The dead time was determined by measuring the retention time of formamide (purity 99.5%, 1.03 x 10^3 mg/I solution) in methanol.

REFERENCE SUBSTANCES
- Identity:
Acetanilide
Phenol
Atrazine
lsoproturon
Naphthalene
Fenthion
Pyrazophos
Alpha endosulfan
Phenanthrene
Diclofop-methyl
DDT

DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 25 μI
- Quantity of reference substances: 25 μI

REPETITIONS
- Number of determinations: 2

Key result

Type:

log Koc

Value:

< 1.25 dimensionless

pH:

6.2

Temp.:

40 °C

Transformation products:

not measured

Reference standards

The retention times of formamide and the reference standards are reported in the following tables.

Dead time	Retention time (mins)		Mean retention time (mins)
	Injection 1	Injection 2
Formamide	3.180	3.182	3.181

Standard	Retention time (mins)		Mean retention time (mins)
	Injection 1	Injection 2
Acetanilide	3.565	3.567	3.566
Phenol	3.572	3.574	3.573
Atrazine	3.923	3.923	3.923
Isoproturon	4.112	4.111	4.112
Naphthalene	4.944	4.947	4.946
Fenthion	6.333	6.326	6.330
Pyrazophos	6.469	6.479	6.474
Alpha endosulfan	8.592	8.593	8.593
Phenanthrene	7.946	7.941	7.944
Diclofop-methyl	8.448	8.453	8.451
DDT	17.906	17.932	17.919

The capacity factor (k) and log₁₀ K_oc values for the reference standards are shown in the following table.

Standard	Capacity Factor (k)	Log10k	Log10Koc
Acetanilide	0.121	-0.917	1.25
Phenol	0.123	-0.909	1.32
Atrazine	0.233	-0.632	1.81
Isoproturon	0.293	-0.534	1.86
Naphthalene	0.555	-0.256	2.75
Fenthion	0.990	-4.460 x 10^-3	3.31
Pyrazophos	1.035	1.503 x 10^-2	3.65
Alpha endosulfan	1.701	0.231	4.09
Phenanthrene	1.497	0.175	4.09
Diclofop-methyl	1.657	0.219	4.20
DDT	4.633	0.666	5.63

Test Sample

The capacity factor (k) and log₁₀K_ocvalues for the sample are shown in the following table.

Injection	Retention time (mins)	Capacity Factor (k)	Log10k	Log10Koc
1	3.075	-3.33 x 10^-2	-	< 1.25
2	3.046	-4.24 x 10^-2	-	< 1.25

Overall  Log₁₀K_oc = < 1.25

Adsorption coefficient = < 17.8

Validity criteria fulfilled:

not specified

Conclusions:

The adsorption coefficient of BHES-100X has been determined to be less than 17.8, log10 Koc < 1.25.

Executive summary:

The adsorption coefficient (K_oc) has been determined to be less than 17.8, log₁₀ K_oc < 1.25, using the OECD draft guideline (July 1997) : Estimation of the Adsorption Coefficient (K_oc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC).

Description of key information

The adsorption coefficient (K_oc) has been determined to be less than 17.8, log₁₀K_oc< 1.25, using the OECD draft guideline (July 1997) : Estimation of the Adsorption Coefficient (K_oc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC).

Key value for chemical safety assessment

Koc at 20 °C:

17.8

Additional information

[LogKoc: 1.25]