Bis(2-hydroxyethyl) sulphone

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

The study was conducted between 6 March 1998 and 17 May 1998

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

other: modified flask method

Specific details on test material used for the study:

Sponsor's identification: BHES-100X
Batch number: 1A0110
Date received: 20 January 1998
Storage conditions: room temperature in the dark

Key result

Water solubility:

>= 94.9 other: % w/w

Conc. based on:

test mat.

Incubation duration:

48 h

Temp.:

20 °C

Remarks on result:

other: test substance was miscible with water in all proportions

Preliminary test

The preliminary estimate of water solubility was > 89.8% w/w.

Definitive test

Observations for each sample are shown in the table below.

Sample	Concentration of test material (% w/w)	Observations
1	5.02	The mixture had formed a colourless, non viscous liquid. No excess test material was visible.
2	50.0	The mixture had formed a pale straw coloured, slightly viscous liquid. No excess test material was visible.
3	94.9	The mixture had formed a off-white, waxy solid (single phase). No excess water visible.

Result : miscible in all proportions

Discussion

The standard flask method specified in Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995 is not applicable to BHES-1 OOX because this substance shows no upper limit for saturation mass concentration in water. A modified procedure was undertaken which would illustrate the complete miscibility of BHES-100X with water.

Conclusions:

BHES-100X has been determined to be miscible in all proportions with water at 20.0 ± 0.5 °C

Executive summary:

The standard flask method specified in OECD Guideline 105 could not be used due to the high saturation levels of BHES-100X in aqueous solution.

In an adaption of the flask method, BHES-100X was found to be miscible in all proportions with water at 20.0 ± 0.5 °C.

Description of key information

The standard flask method specified in OECD Guideline 105 could not be used due to the high saturation levels of BHES-100X in aqueous solution.

In an adaption of the flask method, BHES-100X was found to be miscible in all proportions with water at 20.0 ± 0.5 °C.