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EC number: 232-455-8
CAS number: 8042-47-5
A highly refined petroleum mineral oil consisting of a complex combination of hydrocarbons obtained from the intensive treatment of a petroleum fraction with sulfuric acid and oleum, or by hydrogenation, or by a combination of hydrogenation and acid treatment. Additional washing and treating steps may be included in the processing operation. It consists of saturated hydrocarbons having carbon numbers predominantly in the range of C15 through C50.
a primary dermal irritation study,white rabbits (6 males) were dermally
exposed to 0.5 mL of undiluted Highly refined base oil for 24 hours
occlusively to 2 abraded and 2 unabraded test sites flanking the spine.
Animals were then observed for 24 and 72 hours. Irritation
was scored by the method of Draize (1959).
the 24 and 72 hour observation time points erythema and edema scores
were 0.0 for all sites. In
this study, Highly refined base oil
is not a dermal irritant based on the mean erythema and oedema scores of
study received a Klimisch score of 1 and is classified as reliable
without restriction because it is carried out according to or similar to
guideline study OECD TG 404.
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