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EC number: 232-455-8
CAS number: 8042-47-5
A highly refined petroleum mineral oil consisting of a complex combination of hydrocarbons obtained from the intensive treatment of a petroleum fraction with sulfuric acid and oleum, or by hydrogenation, or by a combination of hydrogenation and acid treatment. Additional washing and treating steps may be included in the processing operation. It consists of saturated hydrocarbons having carbon numbers predominantly in the range of C15 through C50.
In an acute dermal toxicity test, Highly
refined base oil was applied to the abraded skin of New Zealand White
Rabbits (5/sex) at a dose level of 2000 mg/kg under semi-occlusive
conditions for 24 hours of exposure. Animals were observed for 14 days
No mortality or treatment-related lesions
were observed. Three animals lost weight on week two, and one animal
lost weight during the 14-day observation period. No gross lesions were
observed upon necropsy. The acute dermal toxicity LD50 of Highly refined
base oil to male and female New Zealand White Rabbits is greater than
2000 mg/kg and, therefore, is not classifiable under EU guidelines.
This study received a Klimisch score of 2
and is classified as reliable with restrictions because it is an
acceptable, well-documented study report which meets basic scientific
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