Cyclododeca-1,5,9-triene

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Documentation insufficient for assessment

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2003

Report date:

2003

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Cyclododeca-1,5,9-triene

EC Number:

225-533-8

EC Name:

Cyclododeca-1,5,9-triene

Cas Number:

4904-61-4

Molecular formula:

C12H18

IUPAC Name:

cyclododeca-1,5,9-triene

Details on test material:

IUCLID4 Test substance: other TS: 1,5,9-cyclododecatriene, purity 94 % (trans, trans, trans form)
Origin: Tokyo Kasei Kogyo Co., Ltd.

Radiolabelling:

no

Sampling and analysis

Details on sampling:

- Sampling in weeks 1, 2, 4, 6, 8 and 10 (both fish and water)

Test solutions

Vehicle:

yes

Details on preparation of test solutions, spiked fish food or sediment:

- Vehicle / dispersant: HCO-20, HCO-40

Test organisms

Test organisms (species):

Cyprinus carpio

Details on test organisms:

TEST ORGANISMS
- Size of fish: average weight 26.2 g, average total length 9.8 cm
- Lipid content of test organism: 5 % average

Study design

Route of exposure:

aqueous

Test type:

flow-through

Water / sediment media type:

natural water: freshwater

Total exposure / uptake duration:

70 d

Test conditions

Test temperature:

25 °C +/- 1 °C

Details on test conditions:

EXPOSURE CONDITIONS
- Exposure vessel: 100 l glass tank, 1155 l/day flow-through

- Results based on measured concentrations in water

Nominal and measured concentrations:

Concentration of test substance: 1 µg/l, 10 µg/l (nominal)

Reference substance (positive control):

no

Results and discussion

Bioaccumulation factor

Bioaccumulation factor 1

Type:

BCF

Value:

2 630 - 12 500

Basis:

whole body w.w.

Remarks on result:

other: Conc.in environment / dose:10 µg/L

Bioaccumulation factor 2

Type:

BCF

Value:

1 920 - 14 800

Basis:

whole body w.w.

Remarks on result:

other: Conc.in environment / dose:1 µg/L

Depuration

Elimination:

no

Any other information on results incl. tables

- Measured vs nominal concentrations:
  nominal:    1      2      4      6      8     10 weeks
  10 ug/l: 5.54   5.59   6.12   6.49   6.90   6.95 ug/l
   1 ug/l: 0.442  0.511  0.576  0.617  0.650  0.666 ug/l
- Bioconcentration factors
  Range at 10 ug/l: BCF 2630-12500
  Range at  1 ug/l: BCF 1920-14800
  (2 determinations for each concentration and each time point listed above)