Registration Dossier
Registration Dossier
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EC number: 939-516-4 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
There is are no data for polyglycerine. However, data exists for glycerine and polyglycerine polyricinoleate (PGPR).
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
There are no data for polyglycerine. A toxicokinetic study has not been conducted on glycerine. However, glycerine is considered a primordial biomolecule found in all species of living organisms. It is a building block for lipid synthesis and one of the end products of lipid metabolism. Glycerine is also one of the degradation products of glucose metabolism. Toxicokinetic studies have been conducted on polyglycerine polyricinoleate (PGPR) which has been shown to be metabolized in the gastrointestinal tract yielding diglycerine, triglycerine and higher MW glycerine (called Polyglycerine-Heavy in Justification document). Di- and triglycerine are absorbed and excreted unchanged in the urine while the higher MW, by way of increasing number of repeat units of glycerines are not absorbed from the gastrointestinal tract and excreted unchanged in the feces.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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