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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 = 34.64 mg/L at 48 hour (95 % confidence limits 27.86 - 51.91 mg/L), NOEC = 13.3 mg/L, LOEC 27.2 mg/L, OECD 202, EPA OPPTS 850.1010, EU Method C.2, and Japanese guidelines on the testing of new chemical substances, Sipos (2013b)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
34.64 mg/L

Additional information

In the key study (Sipos, 2013b) the acute toxicity of the test material to invertebrates was determined using Daphnia magna in a GLP study performed in accordance with the standardised guidelines OECD 202, EPA OPPTS 850.1010, EU Method C.2, and Japanese guidelines on the testing of new chemical substances.

Twenty Daphnids per concentration were exposed to the test material over 48 hours under freshwater semi-static conditions, and observed for immobilisation at 24 and 48 hours. Animals were exposed at measured concentrations of 4.5, 8.2, 13.3, 27.2 and 36.8 mg/L, analysed using HPLC-MS.

A untreated control was run concurrently for comparison. Potassium dichromate was used as a reference control, and was last tested on 09-10 August 2012.

Under the conditions of the test, the test material was determined to have an EC50 of 34.64 mg/L at 48 hour with 95 % confidence limits of 27.86 - 51.91 mg/L. The NOEC and LOEC were also determined to be 13.3 mg/L and 27.2 mg/L, respectively.