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EC number: 261-332-1
CAS number: 58567-11-6
Table: Details of sample solutions and single results obtained for
different stirring times
Mass of test substance (g)
Volume of water (mL)
Time shaken at 30 °C (hours)
Time equilibrated at 20 °C (hours)
pH value of solution
The water solubility of the substance (ethoxymethoxy)cyclododecane was
tested under GLP in accordance with EU Method A.6. Appropriate amounts
of test substance were weighed into flasks and dissolved in 600 mL of
double-distilled water. Flasks were wrapped in foil. Sample solutions
were then shaken at 30 °C for 24, 48 or 72 hours. After standing at 20
°C for a period of 24 hours, the contents of the flasks were decanted,
avoiding excess test substance then centrifuged at 10000 rpm for 15
minutes and sampled using pipettes. Duplicate aliquots of each sample
were extracted with a single 5 mL aliquot of hexane. Hexane solutions
were taken for analysis of the substance using gas chromatography. The
water solubility of the substance was 1.16 mg/L after 24 hours of
stirring, 1.08 mg/L after 48 hours of stirring and 1.81 mg/L after 72
hours of stirring. The pH value of solutions ranged from 4.83 to 6.75.
The average water solubility of the test substance at 20 °C was 1.12
1.12 mg/L at 20 °C
The water solubility of the substance was 1.12 mg/L at 20 °C in
accordance with OECD 105.
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