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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
25 °C
Vapour pressure:
0.296 Pa

Summary of vapour pressure data

Run

Log10 of vapour pressure at 25 °C

1

-0.528

2

-0.538

3

-0.538

4

-0.529

5

-0.529

6

-0.530

7

-0.518

8

-0.530

9

-0.523

10

-0.527

Mean

-0.529

Vapour pressure at 25 °C in Pa

0.296

Conclusions:
The vapour pressure of the test substance was 0.296 Pa at 25 °C using the vapour pressure balance method.
Executive summary:

The vapour pressure of the test substance registered was determined under GLP using a vapour pressure balance in accordance with EU Method A.4. A sample of the test substance was placed in the balance and a sequence of ten test runs was started after the sample had been under vacuum for about 4.5 hours. Each run was tested over a temperature range from 25 to 35 °C. Linear regression analysis was used to determine the vapour pressure of the substance at 25 °C. The average vapour pressure of the substance at 25 °C as determined in ten runs was 0.296 Pa. The test substance did not change in appearance under the test conditions.

Description of key information

0.296 Pa at 25 °C

Key value for chemical safety assessment

Vapour pressure:
0.296 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure of the substance was 0.296 Pa at 25 °C was determined in accordance with OECD 104 using the vapour pressure balance method.