Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

Inhalation: Remove patient from exposure, keep warm and at rest. Obtain immediate medical attention.
Skin Contact: Take off immediately all contaminated clothing. After contact with skin, wash immediately with plenty of soap and water. Obtain medical attention.
Eye Contact: Immediately irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.
Ingestion: Provided the patient is conscious, wash out mouth with water and give 200-300 ml of water to drink. Do NOT induce vomiting as a First-Aid measure. Obtain immediate medical attention.

Fire-fighting measures

Recommended extinguishing agent: Water spray, foam, dry powder or CO2. Product arising from burning: If involved in a fire, it may burn and emit noxious and toxic fumes.
Unsuitable: Avoid high pressure media which could cause the formation of a potentially explosible dust-air mixture.
Protective equipment: A self contained breathing apparatus and suitable protective clothing should be worn in fire conditions. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:
Ensure full personal protection (including respiratory protection) during removal of spillages.

Environmental Precautions:
Prevent entry into drains, sewers or watercourses. Collect spillage.

Methods and material for containment and cleaning up:
Moisten spillages with water. Transfer to a container for disposal. Wash the spillage area with water. Avoid release to the environment.

Handling and storage

Handling: Avoid contact with skin and eyes. Avoid breathing dust. Wear protective gloves. See Section 8. Minimize dust generation and accumulation. The material may form explosible dust-air mixture if dispersed. Dust clouds are extremely sensitive to ignition by electrostatic discharge or other ignition sources. Ensure good earthing of equipment and personnel.

Storage: Keep container tightly closed. Keep away from heat and direct sunlight. Keep away from moisture.

Transport information

Land transport (ADR/RID)

UN number:
2811
Proper shipping name and description:
TOXIC SOLID, ORGANIC, N.O.S. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
Class:
6.1
Packaging group:
II
Labels:
6.1
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Marine transport (IMDG)

UN number:
2811
Proper shipping name and description:
TOXIC SOLID, ORGANIC, N.O.S. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
Class:
6.1
Packaging group:
II
Labels:
6.1
Marine pollutant
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Air transport ICAO/IATA

UN number:
2811
Proper shipping name and description:
Toxic solid, organic, n.o.s. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
Class:
6.1
Packaging group:
II
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Exposure controls / personal protection

Exposure Controls
Atmospheric levels should be controlled using the principles of good occupational hygiene practice as specified in the workplace risk assessment.Prevent entry into drains, sewers or watercourses.

Occupational exposure controls
Decisions about whether the use of Personal Protective Equipment (PPE) is appropriate, as part of the control strategy, should be based on the workplace risk assessment and should take account of local legislative requirements for selection and use. There are multiple factors that will affect the specific requirements such as amount and concentration of the material, duration of exposure, frequency of exposure etc.

Respiratory protection:
Use an air fed hood for occasional exposures or for repeated exposures use a self-contained breathing apparatus if the risk assessment does not support the selection of other protection.

Skin protection:
Use impervious clothing to protect against direct contact with the substance or for repeated, excessive handling use full chemical protective suit if the risk assessment does not support the selection of other protection. Use impervious protective gloves to protect against direct contact with the substance. If the substance is dissolved or wetted use a glove material that is resistant to the solvent/liquid.

Eye protection:
Use safety glasses to protect against direct contact with the substance if the risk assessment does not support the selection of other protection.

Stability and reactivity

Reactivity:
No known reactivity hazard under normal conditions. The substance is not considered to be explosive.
Chemical stability:
Stable under normal conditions.
Possibility of hazardous reactions:
None known.
Conditions to avoid:
No conditions producing hazardous situations known.
Incompatible materials:
None known.
Hazardous decomposition products:
No hazardous decomposition products are known.

Disposal considerations

Waste treatment methods:
Disposal should be in accordance with local, state or national legislation. Waste, even small quantities, should never be poured down drains, sewers or water courses. This material and/or its container must be disposed of as hazardous waste. Normal waste disposal is via incineration operated by an accredited disposal contractor.
Contaminated Packaging:
Empty container will retain residue. Observe all hazard precautions.