Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 454-140-6 | CAS number: 376608-71-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Inhalation: Remove patient from exposure, keep warm and at rest. Obtain immediate medical attention.
Skin Contact: Take off immediately all contaminated clothing. After contact with skin, wash immediately with plenty of soap and water. Obtain medical attention.
Eye Contact: Immediately irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.
Ingestion: Provided the patient is conscious, wash out mouth with water and give 200-300 ml of water to drink. Do NOT induce vomiting as a First-Aid measure. Obtain immediate medical attention.
Fire-fighting measures
Recommended extinguishing agent: Water spray, foam, dry powder or CO2. Product arising from burning: If involved in a fire, it may burn and emit noxious and toxic fumes.
Unsuitable: Avoid high pressure media which could cause the formation of a potentially explosible dust-air mixture.
Protective equipment: A self contained breathing apparatus and suitable protective clothing should be worn in fire conditions. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Accidental release measures
Personal precautions, protective equipment and emergency procedures:
Ensure full personal protection (including respiratory protection) during removal of spillages.
Environmental Precautions:
Prevent entry into drains, sewers or watercourses. Collect spillage.
Methods and material for containment and cleaning up:
Moisten spillages with water. Transfer to a container for disposal. Wash the spillage area with water. Avoid release to the environment.
Handling and storage
Handling: Avoid contact with skin and eyes. Avoid breathing dust. Wear protective gloves. See Section 8. Minimize dust generation and accumulation. The material may form explosible dust-air mixture if dispersed. Dust clouds are extremely sensitive to ignition by electrostatic discharge or other ignition sources. Ensure good earthing of equipment and personnel.
Storage: Keep container tightly closed. Keep away from heat and direct sunlight. Keep away from moisture.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
- Labels:
- 6.1
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
- Labels:
- 6.1
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (2-(3,4-DIFLUOROPHENYL)-CYCLOPROPYLAMINE MANDELATE)
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Exposure Controls
Atmospheric levels should be controlled using the principles of good occupational hygiene practice as specified in the workplace risk assessment.Prevent entry into drains, sewers or watercourses.
Occupational exposure controls
Decisions about whether the use of Personal Protective Equipment (PPE) is appropriate, as part of the control strategy, should be based on the workplace risk assessment and should take account of local legislative requirements for selection and use. There are multiple factors that will affect the specific requirements such as amount and concentration of the material, duration of exposure, frequency of exposure etc.
Respiratory protection:
Use an air fed hood for occasional exposures or for repeated exposures use a self-contained breathing apparatus if the risk assessment does not support the selection of other protection.
Skin protection:
Use impervious clothing to protect against direct contact with the substance or for repeated, excessive handling use full chemical protective suit if the risk assessment does not support the selection of other protection. Use impervious protective gloves to protect against direct contact with the substance. If the substance is dissolved or wetted use a glove material that is resistant to the solvent/liquid.
Eye protection:
Use safety glasses to protect against direct contact with the substance if the risk assessment does not support the selection of other protection.
Stability and reactivity
Reactivity:
No known reactivity hazard under normal conditions. The substance is not considered to be explosive.
Chemical stability:
Stable under normal conditions.
Possibility of hazardous reactions:
None known.
Conditions to avoid:
No conditions producing hazardous situations known.
Incompatible materials:
None known.
Hazardous decomposition products:
No hazardous decomposition products are known.
Disposal considerations
Waste treatment methods:
Disposal should be in accordance with local, state or national legislation. Waste, even small quantities, should never be poured down drains, sewers or water courses. This material and/or its container must be disposed of as hazardous waste. Normal waste disposal is via incineration operated by an accredited disposal contractor.
Contaminated Packaging:
Empty container will retain residue. Observe all hazard precautions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
