Registration Dossier
Registration Dossier
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EC number: 454-140-6 | CAS number: 376608-71-8
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Guideline:
- other: Air elutriation
- Principles of method if other than guideline:
- HSE, 2000 MDHS 14
ISO 7708:1995(E) - GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- -
- EC Number:
- 454-140-6
- EC Name:
- -
- Cas Number:
- 376608-71-8
- Molecular formula:
- C9H9F2N*C8H8O3
- IUPAC Name:
- (1R)-2-(3,4-difluorophenyl)cyclopropan-1-aminium (2R)-2-hydroxy-2-phenylacetate
- Reference substance name:
- trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
- IUPAC Name:
- trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
Constituent 1
Constituent 2
Results and discussion
Particle size
- Percentile:
- D50
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- <= 115 µm
- Distribution:
- 4.12 %
- No.:
- #2
- Size:
- < 15 µm
- Distribution:
- 0.13 %
Applicant's summary and conclusion
- Conclusions:
- It was apparent that some of the test substance was capable of becoming airborne under the conditions of the test, 4.12% being less than or equivalent to 115 µm aerodynamic equivalent diameter (AED). Eluted material having an AED of less than 15 µm can be considered as respirable and represented 0.13% by weight. Therefore, C3RO is considered to be of very low inhalability and respirability.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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