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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Guideline:
other: Air elutriation
Principles of method if other than guideline:
HSE, 2000 MDHS 14
ISO 7708:1995(E)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
454-140-6
EC Name:
-
Cas Number:
376608-71-8
Molecular formula:
C9H9F2N*C8H8O3
IUPAC Name:
(1R)-2-(3,4-difluorophenyl)cyclopropan-1-aminium (2R)-2-hydroxy-2-phenylacetate
Constituent 2
Reference substance name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
IUPAC Name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate

Results and discussion

Particle size
Percentile:
D50
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Particle size distribution at different passagesopen allclose all
No.:
#1
Size:
<= 115 µm
Distribution:
4.12 %
No.:
#2
Size:
< 15 µm
Distribution:
0.13 %

Applicant's summary and conclusion

Conclusions:
It was apparent that some of the test substance was capable of becoming airborne under the conditions of the test, 4.12% being less than or equivalent to 115 µm aerodynamic equivalent diameter (AED).  Eluted material having an AED of less than 15 µm can be considered as respirable and represented 0.13% by weight. Therefore, C3RO is considered to be of very low inhalability and respirability.