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Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
454-140-6
EC Name:
-
Cas Number:
376608-71-8
Molecular formula:
C9H9F2N*C8H8O3
IUPAC Name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
Constituent 2
Reference substance name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
IUPAC Name:
trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate

Results and discussion

Water solubility
Water solubility:
> 6 850 - < 7 150 mg/L
Temp.:
25 °C
pH:
> 5.71 - < 5.78
Details on results:
Result by UV Analysis : 7000 ± 150mg/l at 25°C ± 1°C. Test 1 : 6995mg/l at 25°C ± 1°C. Test 2 : 6983mg/l at 25°C ± 1°C. Test 3 : 6958mg/l at 25°C ± 1°C. Test 4 : 6880mg/l at 25°C ± 1°C. Test 5 : 7095mg/l at 25°C ± 1°C.

Applicant's summary and conclusion