Registration Dossier
Registration Dossier
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EC number: 454-140-6 | CAS number: 376608-71-8
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: EU method C.7
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- -
- EC Number:
- 454-140-6
- EC Name:
- -
- Cas Number:
- 376608-71-8
- Molecular formula:
- C9H9F2N*C8H8O3
- IUPAC Name:
- (1R)-2-(3,4-difluorophenyl)cyclopropan-1-aminium (2R)-2-hydroxy-2-phenylacetate
- Reference substance name:
- trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
- IUPAC Name:
- trans-(1R,2S)-2-(3,4-difluorophenyl-cyclopropanaminium (2R)- 2-hydroxy-2-phenylethanoate
Constituent 1
Constituent 2
Results and discussion
Dissipation DT50 of parent compound
- pH:
- 7
- Temp.:
- 70 °C
- DT50:
- 21.5 h
Applicant's summary and conclusion
- Conclusions:
- The rate of hydrolysis (t1/2)of mandelic acid at the environmentally relevant temperature of 25 deg C has been estimated to be
- Executive summary:
Comments:
Estimated half-life of C3RO at 25 degC:
pH 7: 2302 hours (or 96 days)
pH 9: 489 hours (or 20 days)
Test concentration:
Nominal concentration of 350 mg/l
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