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EC number: 223-754-4 | CAS number: 4051-63-2
Since no data of acute toxicity on fish, daphnia and algae for the described pigment are available, a read-across to a similar pigment (CAS 81-77-6) is used to cover these endpoints. Since the molecular structure and the physico-chemical properties of the pigments are very similar, the available studies are sufficient to cover the aquatic toxicity endpoints. Both pigments are of low solubility in water and in octanol. They do not contain functional groups that are susceptible to pH dependent hydrolysis at environmentally relevant pH. The pigments are generally not readily biodegradable and additionally adsorption to the solid soil phase is not expected. Due to the low logPow and the high molecular weight of the pigments, bioaccumulation is not expected. Therefore, this read-across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read-across approach as it is explained within the analogue justification in the Annex.
For the analogue substance acute aquatic toxicity data on all three trophic levels are available. This includes a study for the acute toxicity on the golden orfe Leuciscus idus, one study on the mortality of the waterflea Daphnia magna and one study of the toxicity on the green algae Desmodesmus subspicatus. After exposure to the pigment, no effects on aquatic organisms occurred within the range of water solubility. These results confirm the expectation, that the described pigment is considered to be essentially not bioavailable, due to the large molecular size together with the negligible low solubility.
No data on long-term toxicity are available. The hazard assessment of the substance reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, and for reasons of animal welfare long-term toxicity testing in fish and daphnia is not provided.
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