Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
Please refer to the category justification provided in the category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Alcohols, C9-11, branched and linear, ethoxylated, sulfates, ammonium salts
EC Number:
500-464-9
EC Name:
Alcohols, C9-11, branched and linear, ethoxylated, sulfates, ammonium salts
Cas Number:
160901-27-9
Molecular formula:
C9-11H19-23(OCH2CH2)1-2.5SO4NH4
IUPAC Name:
Alcohols C9-11, ethoxylated (1-2,5 EO) sulphated, ammonium salts

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Remarks on result:
other: Read-across based on all available data on acute dermal toxicity in the Alkyl Ether Sulfates (AES) category.

Any other information on results incl. tables

For a detailed assessment of the acute dermal toxicity of the Alkyl Ether Sulfates (AES) category, please refer to the category justification attached to the category object.

Applicant's summary and conclusion

Interpretation of results:
other: CLP/EU GHS criteria not met, no classification required according to Regulation (EC) No 1272/2008
Conclusions:
Applying read-across based on grouping of substances (category approach), a dermal LD50 > 2000 mg/kg bw is predicted for the target substance.
Executive summary:

The available data on acute dermal toxicity in the Alkyl Ether Sulfates (AES) category reveal a dermal LD50 value > 2000 mg/kg bw. Based on the category approach, a dermal LD50 value > 2000 mg/kg bw is predicted for the target substance. As explained in the category justification, the differences in molecular structure and composition between the target substance and the members of the AES category are unlikely to lead to differences in the toxicological properties with respect to acute dermal toxicity.