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EC number: 500-464-9 | CAS number: 160901-27-9 1 - 2.5 moles ethoxylated
The chemical safety assessment carried out according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
There are no long-term fish studies available for AES (C9-11, 1-2.5EO) NH4 (CAS 160901-27-9). Based on the available acute and chronic toxicity data of alkyl ethoxy sulfates, fish cannot be identified as the most sensitive taxonomic group.According to the “Guidance on information requirements and chemical safety assessment Chapter R.7b: Endpoint specific guidance, R.22.214.171.124” (ECHA, 2008), long-term testing of fish should only be conducted if it represents the most sensitive taxonomic group. The Guidance Document states that if invertebrates are likely to be more sensitive than fish and algae or the relative sensitivity of invertebrates cannot be predicted, long-term testing on Daphnia sp. should be preferred instead of fish.
For the structural comparable AES (C8-10, 1-2.5EO) NH4 the results of a chronic invertebrates study carried out with Daphnia magna are available. In this test a NOEC of 5.3 mg a.i./L was determined. Since for the longer carbon chain lengths AES the available acute and chronic results of fish and daphnids are in the same range, it can be assumed that for the shorter carbon chain lengths AES the results of a long-term fish study will not be significantly different from the results of the available chronic Daphnia study. Hence, based on the information discussed above and due to animal welfare reasons, no further long-term test with fish is proposed.
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