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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

An OECD 211 (daphnia reproduction) guideline study on EC 283-392-8 was used for read-across. The 21 day IC50s for neonate production, adult daphnid length and adult daphnid weight were > 0.8 mg/L based on nominal loading rates and >0.53 mg/L based on measured concentrations. The NOECs were 0.4 mg/L nominal (0.26 mg/L measured) for reproduction and 0.8 mg/L nominal (0.53 measured) for both daphnid length and daphnid weight, the latter being the highest level tested. The LOECs were 0.8 mg/L nominal for reproduction and >0.8 mg/L nominal for daphnid length and weight.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.4 mg/L

Additional information

Read-across from other, structurally closely related ZDDPs is justified because of structural similarity and analogy of properties and effects. These are apparent from the physico-chemical properties, ecotoxicity, mammalian toxicity and fate, and supported by predictions using models.