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EC number: 701-326-2
CAS number: -
In an acute oral toxicity study performed
according to the OECD test guideline No. 420 and in compliance with GLP,
groups of fasted, eight to twelve weeks of age Wistar (RccHanTM:WIST)
female rats were given a single oral dose of ST 10 C 08 as a suspension
in Arachis oil BP. Following a sighting test using one animal at a dose
level of 2000 mg/kg bw, an additional four fasted female animals were
given a single oral dose of test item, at the same dose level. Clinical
signs and bodyweight development were monitored during the study. All
animals were subjected to gross necropsy.
Oral LD50 Females > 2000 mg/kg
There were no deaths during the study.
Ataxia and/or hunched posture were noted in all animals during the day
of dosing. All animals showed expected gains in bodyweight. No
abnormalities were noted at necropsy.
Under the test conditions, ST 10 C 08 is not
classified as toxic if swallowed according to the Regulation (EC) No.
1272/2008 (CLP) and to the GHS.
This study is considered as acceptable and
satisfies the requirement for acute oral toxicity endpoint.
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