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EC number: 701-326-2 | CAS number: -
According to section R.184.108.40.206., Chapter R.7c of the ECHA Guidance on information requirements and chemical safety assessment (version 3.0, June 2017), the registered substance should be classed as a soil hazard category 3 (high adsorption of the substance in soil with log Kow > 5 and Koc > 5000; and not very toxic to aquatic organisms).
In the context of an integrated testing strategy for soil toxicity, the Guidance advocates performing an initial screening assessment based upon the Equilibrium Partitioning Method (EPM), together with a confirmatory long-term soil toxicity test (e.g. one limit test with the most sensitive organism group as indicated from aquatic toxicity data). Indeed, for substances that show a high potential to partition to soil, like the registered substance, long-term exposure of terrestrial organisms is possible and should be assessed. The choice of test (invertebrate / plant / micro-organism) should be based on all the information available. For the registered substance, the most sensitive organism group in aquatic toxicity data is the aquatic invertebrates. Therefore, an invertebrate assay is chosen to assess the long-term soil toxicity.
Hence, a testing proposal is included in the dossier to conduct an earthworm reproduction test, according to OECD Guideline 222. A simplified study with a limit test is proposed in a first step, as suggested in the ECHA Guidance, to confirm the absence of risk for soil organisms observed in the screening assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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