Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 425 (Acute Oral Toxicity: Up-and-Down Procedure)
GLP compliance:
no
Test type:
up-and-down procedure
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(methoxymethyl)-3-methyl-aniline
EC Number:
821-826-5
Cas Number:
1472650-01-3
Molecular formula:
C9 H13 N O
IUPAC Name:
2-(methoxymethyl)-3-methyl-aniline
Test material form:
liquid

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage
Doses:
2000 mg/kg

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw

Applicant's summary and conclusion