Registration Dossier

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 471 (Bacterial Reverse Mutation Assay)
GLP compliance:
no
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(methoxymethyl)-3-methyl-aniline
EC Number:
821-826-5
Cas Number:
1472650-01-3
Molecular formula:
C9 H13 N O
IUPAC Name:
2-(methoxymethyl)-3-methyl-aniline
Test material form:
liquid

Method

Metabolic activation:
with and without

Results and discussion

Additional information on results:
negative with and without metabolic activation

Applicant's summary and conclusion