Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Reliable predicted value obtained by the OECD QSAR Toolbox using trend analysis within category members.The prediction fulfilling the OECD criteria for the validation of QSAR models with respect to • a defined endpoint • unambiguous algorithm • a defined domain of applicability • appropriate measure of goodness-of-fit, robustness and predictivity

Data source

Reference
Reference Type:
other: OECD QSAR Toolbox Report
Title:
Unnamed
Year:
2018

Materials and methods

Principles of method if other than guideline:
Calculation using QSAR Toolbox based on trend analysis within category members.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(methoxymethyl)-3-methyl-aniline
EC Number:
821-826-5
Cas Number:
1472650-01-3
Molecular formula:
C9 H13 N O
IUPAC Name:
2-(methoxymethyl)-3-methyl-aniline
Test material form:
liquid

Sampling and analysis

Analytical monitoring:
not required

Test organisms

Test organisms (species):
not specified

Study design

Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
140 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion