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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Acutely harmful to aquatic algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
70.4 mg/L
EC10 or NOEC for freshwater algae:
41 mg/L

Additional information

A GLP-guideline study according to OECD 201 is available to assess the toxicity of 2-[2-(dimethylamino)ethoxy]-N-methylethanamine (TMAEE, CAS 93240 -93 -8) towards aquatic algae. As test organism the green alga Pseudokirchneriella subcapitata was used. It was exposed to TMAEE under static freshwater conditions for 72 hours. The test concentrations were analytically verified and deviated less than 20% from the nominal concentrations. The pH values were not adjusted and ranged from 7.9 to 9.6 (0 h) and from 8.1 to 8.6 (72 h) in the treatments. All validity criteria were fulfilled. An 72 -h ErC50 of 70.4 mg/L (95% CL: 37.0 - 99.2 mg/L) and an 72 -h ErC10 of 41.0 mg/L (95% CL: 32.4 to 98.5 mg/L) were determined based on nominal test concentrations (BASF SE, 2019, report no.: 60E0034/19X015).

In conclusion, TMAEE (CAS 93240-93-8) is assessed to be acutely harmful to algae.