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Toxicity to microorganisms

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Description of key information

The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
720 mg/L

Additional information

The assessment of the toxicity of TMAEE (CAS 93240-93-8) to aquatic microorganisms is based on read-across to experimental data availableforBDMAEE (CAS 3033‑62-3).The toxicity of BDMAEE to microorganisms was tested in two assays:

- In the key study, conducted similar to OECD 209, an activated sludge respiratory inhibition test was performed using a static freshwater test system; the nominal test substance concentrations were 360 mg/L and 720 mg/L. The effect concentration derived in this test (respiration rate assessment) was an EC20 of > 720 mg/L after 30 min (BASF AG, 1987).

In a second test, the toxicity of the source chemical BDMAEE to Vibrio fisheri was checked using the ‘Microtox’ method in a static saltwater test. Nominal test substance concentrations used were 1406, 2812, 5625, 11250, 22500 and 45000 mg/L. The effect concentrations derived in the test (light emission assessment) were EC50 = 27,500 mg/L after 5 min, EC50 = 21,000 mg/L after 15 min and EC50 = 16,750 mg/L after 30 minutes (Huntsman, 1997). However, in accordance with Table R.10-6 of Regulation EC no. 1907/2006, single-species tests based on a marine species are of limited relevance for STP functioning. Therefore, the study was disregarded in terms of chemical safety assessment.

Based on the experimental read-across data from the source substance it can be concluded that the inhibition of the degradation activity of activated sludge is not anticipated when TMAEE (CAS 93240‑93-8) is introduced in appropriately low concentrations.