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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2018-03-09 to 2018-04-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
Batch No.: 20170707
Purity: 99.13%
Mass median aerodynamic diameter:
61.6 µm
Geometric standard deviation:
1.13
Percentile:
D10
Mean:
7.47 µm
St. dev.:
0.081
Key result
Percentile:
D50
Mean:
61.6 µm
St. dev.:
1.13
Percentile:
D90
Mean:
352 µm
St. dev.:
7.8

Coefficient of variation for D50 is less than 3%; D10 and D90 are less than 5%. Thus repeatability of the characteristic particles in the size distribution are within the acceptable limits as per the ISO 13320-1 test standard.

Conclusions:
The D50 of this substance is 61.6 μm, D10 is 7.47 μm, D90 is 352.0 μm.
13.69 % by volume of sample was seen to be < 10.00 μm.
Executive summary:

The test is conducted in accordance with ISO 13320:2009 "Particle Size Analysis – Laser Diffraction Methods", 2009 and CIPAC MT 187 "Particle Size Analysis by Laser Diffraction", Handbook K, 2007 to determine the particle size distribution of test item.

The D50 of this substance is 61.6 μm, D10 is 7.47 μm, D90 is 352.0 μm.

13.69 % by volume of sample was seen to be < 10.00 μm.

Description of key information

The D50 of this substance is 61.6 μm, D10 is 7.47 μm, D90 is 352.0 μm.

Additional information