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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method
Water solubility:
< 0.003 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
6.5
Details on results:
The concentration of the sample was shown to be below the limit of quantification at both flow rates.

Date/Time

Temp (oC)

Column A

 

 

Column B

 

 

 

 

Flow Rate (mL/min)

Time (min)

Calculated Conc (mg/L)

Flow rate (mL/min)

Time (min)

Calculated Conc (mg/L)

16/10/17

07:50

20+/-0.5oC

1

40

< 0.0025

2

40

0.0172

16/10/17

08:10

20+/-0.5oC

1

No Sample at time point

2

60

< 0.0025

16/10/17

08:30

20+/-0.5oC

1

80

< 0.0025

2

80

< 0.0025

16/10/17

08:50

20+/-0.5oC

1

No Sample at time point

2

100

< 0.0025

16/10/17

09:10

20+/-0.5oC

1

120

< 0.0025

2

120

< 0.0025

16/10/17

09:30

20+/-0.5oC

1

No Sample at time point

2

140

< 0.0025

16/10/17

09:50

20+/-0.5oC

1

160

< 0.0025

2

160

< 0.0025

16/10/17

10:10

20+/-0.5oC

1

No Sample at time point

2

180

< 0.0025

16/10/17

10:30

20+/-0.5oC

1

200

< 0.0025

2

200

< 0.0025

Conclusions:
The water solubility of the substance is < 0.0025 mg/L.
Executive summary:

In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.

Description of key information

In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.

Key value for chemical safety assessment

Water solubility:
0.003 mg/L
at the temperature of:
20 °C

Additional information