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Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 October 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- column elution method
- Water solubility:
- < 0.003 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 6.5
- Details on results:
- The concentration of the sample was shown to be below the limit of quantification at both flow rates.
- Conclusions:
- The water solubility of the substance is < 0.0025 mg/L.
- Executive summary:
In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.
Reference
Date/Time |
Temp (oC) |
Column A |
|
|
Column B |
|
|
|
|
Flow Rate (mL/min) |
Time (min) |
Calculated Conc (mg/L) |
Flow rate (mL/min) |
Time (min) |
Calculated Conc (mg/L) |
16/10/17 07:50 |
20+/-0.5oC |
1 |
40 |
< 0.0025 |
2 |
40 |
0.0172 |
16/10/17 08:10 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
60 |
< 0.0025 |
|
16/10/17 08:30 |
20+/-0.5oC |
1 |
80 |
< 0.0025 |
2 |
80 |
< 0.0025 |
16/10/17 08:50 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
100 |
< 0.0025 |
|
16/10/17 09:10 |
20+/-0.5oC |
1 |
120 |
< 0.0025 |
2 |
120 |
< 0.0025 |
16/10/17 09:30 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
140 |
< 0.0025 |
|
16/10/17 09:50 |
20+/-0.5oC |
1 |
160 |
< 0.0025 |
2 |
160 |
< 0.0025 |
16/10/17 10:10 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
180 |
< 0.0025 |
|
16/10/17 10:30 |
20+/-0.5oC |
1 |
200 |
< 0.0025 |
2 |
200 |
< 0.0025 |
Description of key information
In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.003 mg/L
- at the temperature of:
- 20 °C
Additional information
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