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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 February 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
non GLP
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
30 °C
Remarks on result:
other: pH was not reported
Details on results:
The test substance did not elute within the the retention range of the reference standards, thereore the logPow was not calculated but given a limit value LogPow of greater than 6.5 .

Retention Time and Known Partition Coefficient Values

Standard name

Mean Retention time

Mean Log Capacity Factor = Log k’

Log POWa

SodiumNitrate[MK1] 

1.88

 

0

Acetanilide

2.125

-0.8851

1

Toluene

4.24

0.0988

2.7

Naphthalene

5.175

0.2437

3.6

Biphenyl

7.085

0.4423

4

Phenanthrene

10.11

0.6412

4.5

DDT

23.31

1.0569

6.5


a) Values taken from OECD Guideline 117

regression line y= 0.3465x - 1.0215 (R² = 0.9416) calculated based on the measurements in this study

 

Conclusions:
The logKow of the substance is > 6.5
Executive summary:

In a study using the HPLC method, the test substance did not elute within the retention range of the reference standards, therefore the logPow was not calculated but given a limit value LogPow of greater than 6.5.

Description of key information

In a study using the HPLC method, the test substance did not elute within the retention range of the reference standards, therefore the logPow was not calculated but given a limit value LogPow of greater than 6.5.

Key value for chemical safety assessment

Log Kow (Log Pow):
6.5
at the temperature of:
30 °C

Additional information