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EC number: 947-986-7
CAS number: -
The substance was tested for skin irritation in the EpiDermTM model
according to OECD 439. 30 uL of the substance, positive control (5% SDS)
and negative control (PBS) was applied to the tissue for 60 minutes (25
minutes at room temperature and 35 minutes at 37°C, 5% CO2) and
thereafter incubated for 42 hour post-dose at 37°C, 5% CO2. The
substance did not interfere by colour or by direct MTT reduction. Tissue
viability was 106.9% of negative controls, while validity criteria were
evaluated to be met. The substance is concluded to be non-irritant.
The substance was tested for eye irritation in the EpiOcular TM Eye
Irritation model according to OECD 492. 50 uL of the substance, positive
control (methyl acetate) and negative control (H2O) was applied to the
tissue for 30 minutes, followed by a 12 minutes post-treatment immersion
at 37°C, 5% CO2 and thereafter incubated for 2 hour post-dose at 37°C,
The substance did not interfere by colour or by direct MTT reduction.
Tissue viability was 100.1% of negative controls, while validity
criteria were met. The substance is concluded to be non-irritant.
Mean of OD
SD of OD
Mean of viability (%)
SD of viability (%)
mean of OD
Based on the information available the substance does not need to be
classified for skin- and eye irritation according to EC Regulation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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