2-Propenoic acid, homopolymer

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2016-10-27 to 2017-03-21

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

2015-07-28

Type of method:

flask method

Specific details on test material used for the study:

- Composition of test material: 2-carboxyethyl acrylate oligomers (= homopolymers of acrylic acid + 2-carboxyethyl acrylate) and acrylic acid
- Analytical purity: >=99%
- Purity test date: 24 August 2016
- Lot/batch No.: BA5H22021
- Expiration date of the lot/batch: 24 August 2017
- Appearance: Colourless limpid liquid
- Storage: In darkness at room temperature

For the analysis, a different batch of the test item (BA5E47549) was used as reference item.

Key result

Water solubility:

> 104 g/L

Conc. based on:

other: acrylic acid monomers

Temp.:

20 °C

pH:

ca. 3.23

Key result

Water solubility:

> 488 g/L

Conc. based on:

other: 2-carboxyethyl acrylate oligomers

Temp.:

20 °C

pH:

ca. 3.23

Key result

Water solubility:

> 546 g/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

ca. 3.23

Details on results:

The solubility in water of the test item is > 546 g/L at 20.0°C ± 1.0°C.

Preliminary test

Through the serial volume addition of water to the test item, the following table shows the solubility in water of acrylic acid monomers and 2-carboxyethyl acrylate oligomers at 21.0 °C ± 1.0 °C.

Weight of test item (g)	Volume of water (mL)	Solubility (g/L)
0.09855	0.1	Cloudy	/
	0.5	Cloudy	/
	1	Cloudy	> 100

 

Main test

For acrylic acid monomers: 

	Reference of test solutions	Peak area (area units)	Conc. (mg/L)	Mean Conc. (mg/L)	Dil. factor	Final conc. in acrylic acid monomers (g/L)	Final conc. in test item (g/L)	pH at 19°C
				C	Df	Cf	Cf1
After 24h	16-217 2A dil 16-217 2A dil	9.2401 9.2232	5.13 5.12	5.13	20000	102.6	539.8	3.27
	16-217 2B dil 16-217 2B dil	9.3070 9.2943	5.17 5.16	5.17	20000	103.3	543.8	3.24
After 48h	16-217 2C dil 16-217 2C dil	9.6673 9.6742	5.37 5.37	5.37	20000	107.4	565.2	3.24
	16-217 2D dil 16-217 2D dil	9.2982 9.3001	5.16 5.17	5.17	20000	103.3	543.7	3.22
After 72h	16-217 2E dil 16-217 2E dil	9.2730 9.2388	5.15 5.13	5.14	20000	102.8	541.2	3.23
	16-217 2F dil 16-217 2F dil	9.2432 9.2166	5.13 5.12	5.13	20000	102.5	539.7	3.19
					Mean	104	546
					SD	2	10
					RSD (%)	1.79	1.79

 

For 2 -carboxyethyl acrylate oligomers

	Reference of test solutions	Peak area (area units)	Conc. (mg/L)	Mean Conc. (mg/L)	Dil. factor	Final conc. in  2-carboxyethyl acrylate oligomers (g/L)	Final conc. in test item (g/L)	pH at 19°C
				C	Df	Cf	Cf1
After 24h	16-217 2A dil 16-217 2A dil	24.6232 24.4973	24.28 24.16	24.2	20000	484.3	578.0	3.27
	16-217 2B dil 16-217 2B dil	24.6516 24.7324	24.31 24.38	24.3	20000	486.9	581.0	3.24
After 48h	16-217 2C dil 16-217 2C dil	25.6200 25.7176	25.24 25.34	25.3	20000	505.8	603.6	3.24
	16-217 2D dil 16-217 2D dil	24.6047 24.6973	24.26 24.35	24.3	20000	486.1	580.1	3.22
After 72h	16-217 2E dil 16-217 2E dil	24.5501 24.5982	24.21 24.25	24.2	20000	484.6	578.3	3.23
	16-217 2F dil 16-217 2F dil	24.5364 24.4194	24.19 24.08	24.1	20000	482.8	576.1	3.19
					Mean	488	583
					SD	9	10
					RSD (%)	1.77	1.77

  

Conclusion

The following table shows the solubility in water of the test item performed at 20.0°C ± 1.0°C.

Solubility in water test item (g/L)	Expressed as acrylic acid monomers	Expressed as 2-carboxyethyl acrylate oligomers	Expressed as test item
	> 104	> 488	> 546

Conclusions:

The solubility in water of the test item was assessed to be > 546 g/L at 20.0°C ± 1.0°C.

Executive summary:

The water solubility of the REACH substance was determined in a GLP-compliant study performed in accordance with EC A.6 method and OECD Guideline No. 105. The solubility in water of the test item was assessed to be > 546 g/L at 20.0°C ± 1.0°C.

Description of key information

The water solubility of the REACH substance was determined in a GLP-compliant study performed in accordance with EC A.6 method and OECD Guideline No. 105. The solubility in water of the test item was assessed to be > 546 g/L at 20.0°C ± 1.0°C.

Key value for chemical safety assessment

Water solubility:

546 g/L

at the temperature of:

20 °C

Additional information

The water solubility of the REACH substance was determined in a GLP-compliant study performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and is selected as a key study for the endpoint.