Reaction mass of ammonium(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) hydrogen phosphate and ammonium bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) phosphate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

Because FS-8250 is an aqueous emulsion it was difficult to visually pick up solubility; so it was opted to explore %Transmittance measurements of a series of dilutions of FS-8250. %T plotted against concentration did not yield %T's over 98% until about 0.2%

Deviations:

yes

Remarks:

as in remarks

Principles of method if other than guideline:

Quantitiative analysis for the mono and di phosphate esters was by LC/ms via direct flow injection analysis (FIA)
Internal standards of the mono and di phosphate esters of 2-ethylhexyl alcohol were used

GLP compliance:

no

Type of method:

other: LC/MS

Specific details on test material used for the study:

Thetawet FS-8250 is a 28% actives aqueous emulsion, water dispersible, low foam anionic fluorosurfactant
The active components are ammonium salts of [Mono & Di] 2-(Perfluorohexyl)ethyl-Phosphate. Found at ca. 10% and 18% respectively in the final product
Lot number: w17061205
Manufacturing date: 6/12/2017
Manufacturing Location: 103 Walnut Grove Road, Cartersville, GA 30120

Key result

Water solubility:

>= 683 - <= 6 829 mg/L

Conc. based on:

act. ingr. (total fraction)

Temp.:

22 °C

pH:

8.78

Details on results:

The solubility of individual components of the reaction mixture (Mono[2-(perfluorohexyl)ethyl] Phosphate and Bis[2-(perfluorohexyl)ethyl] Phosphate) were determined separately.
These were reported as 6829 mg/l for the mono species and 683 mg/l for the bis species.

Description of key information

This substance is a product by process; a mixed phosphate ester from 2-(Perfluorohexyl)ethanol

The active components are ammonium salts of [Mono & Di] 2-(Perfluorohexyl)ethyl-Phosphate

It is a 28% actives aqueous emulsion. The ratio of the above products is ca. 1 : 2 respectively. In the formulated emulsion, analytical results typically fall around 10% for the mono-ester and 20% for the di-ester.

It was opted to conduct the Kow study on the product mixture for two reasons

1.The substance is a product by process, so the two component mixture is the delivered product

2. Manipulation of the product through drying or separation can alter the product

Key value for chemical safety assessment

Water solubility:

683 mg/L

at the temperature of:

22 °C

Additional information

This value is determined for the Bis[2-(perfluorohexyl)ethyl] Phosphate component of this reaction mixture, which is the major component.