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Physical & Chemical properties

Particle size distribution (Granulometry)

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Link to relevant study record(s)

Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187 Particle Size Analysis by Laser Diffraction
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Specific details on test material used for the study:
Batch no.: P816P001
Expiry date: 03-01-2019
Storage: room temperature (20+/-5°C), away from light and humidity
Percentile:
D10
Mean:
37.2 µm
St. dev.:
0.6
Key result
Percentile:
D50
Mean:
133.3 µm
St. dev.:
1.74
Percentile:
D90
Mean:
431.9 µm
St. dev.:
47.54
Conclusions:
The L-histidine sample has a median particle size D50 = 133.3 µm.
Executive summary:

The median particle size of a sample of L-histidine was determined by laser diffraction in accordance with OECD guideline 110.

The D50 was found to be 133.3 µm.

Description of key information

The median particle size of a sample of L-histidine was determined by laser diffraction in accordance with OECD guideline 110.

The D50was found to be 133.3 µm.

Additional information