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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Adsorption / desorption

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Administrative data

Endpoint:
adsorption / desorption
Remarks:
other: QSAR
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
QSAR prediction.

Data source

Reference
Reference Type:
other: QSAR
Title:
KOCWIN v2.00
Author:
EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation.
Year:
2000
Bibliographic source:
http://www.epa.gov/opptintr/exposure/pubs/episuite.htm

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Histidine
EC Number:
200-745-3
EC Name:
Histidine
Cas Number:
71-00-1
Molecular formula:
C6H9N3O2
IUPAC Name:
histidine

Results and discussion

Adsorption coefficientopen allclose all
Type:
log Koc
Value:
-1.304
Remarks on result:
other: Estimated from the Log Kow
Type:
log Koc
Value:
1
Remarks on result:
other: Estimated from the MCI method.

Applicant's summary and conclusion

Conclusions:
Depending on the calculation method used, the log Koc was found to be -1.3040 (based on log Kow) or 1.00 (based on MCI method).
Executive summary:

The log Koc was calculated by EpiSuite's KOCWIN model.

The suitability of the model was assessed and it was concluded that L-histidine is considered to be inside the applicability domain of the EpiSuite KOCWIN model.

Depending on the calculation method used, the log Koc was found to be -1.3040 (based on log Kow) or 1.00 (based on MCI method).