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EC number: 200-745-3
CAS number: 71-00-1
L-Histidine -hydrochlorid caused a histamine-like reduction in blood pressure in anesthesized cats.
In the study of Leuschner and Neumann (1982) the effect of
L-histidine-hydrochlorid was examined on histamine-like reduction of the
blood pressure in anesthetized cats. The method used was the Depressor
Intravenous injection of 3 mg L-histidine-HCL bw caused a reaction
comparable to 0.1 µg Histamine/ kg bw intravenous.
1.0 mg L-histidine-HCL bw intravenous also caused a reduction in blood
pressure. When comparing to a previous histamine reaction this is within
the 50% area of both animals. Considering the experimental conditions
the concentration of 1.0 mg L-histidine-HCL/kg bw showed the expected
histamine-like reduction in blood pressure.
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